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Invitrogen™ STAT5 alpha/beta Monoclonal Antibody (ST5-8F7)
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Catalog No. 335900
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Catalog No. Quantity
33-590-0 100 μg
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Catalog No. 33-590-0 Supplier Invitrogen™ Supplier No. 335900
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Description

Mouse Monoclonal Antibody

STAT5 alpha/beta Monoclonal Antibody for ELISA, ICC/IF, Western Blot

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor-associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of, many cell ligands, such as IL-2, IL-3, IL-7, GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/ BCL-X(L), which suggests the antiapoptotic function of this gene in cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STAT5 alpha/beta
Applications ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone ST5-8F7
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene STAT5A
Gene Accession No. P42229, P42230, P42232, P51692, P52632, Q62771
Gene Alias AA959963; Mammary gland factor; mammary gland factor STAT5A; mammary gland factor STAT5B; mammary gland factor; transcription factor; MGF; Mpf; signal transducer and activator of transcription 5; Signal transducer and activator of transcription 5a; Signal transducer and activator of transcription 5B; STA5B; STAT; STAT5; Stat5a; Stat5b; transcription factor STAT5B
Gene Symbols STAT5A, STAT5B
Host Species Mouse
Immunogen A peptide corresponding to a conserved amino acid sequence found near the carboxy-terminus of murine STAT5. This peptide encompasses the conserved C-terminal tyrosine phosphorylation site (Y-694) of murine STAT5.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20850, 20851, 24918, 25126, 6776, 6777
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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