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Invitrogen™ STAT6 Polyclonal Antibody
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Catalog No. PIPA534814
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100 μL
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PIPA534814 100 μL
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Catalog No. PIPA534814 Supplier Invitrogen™ Supplier No. PA534814
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HepG2, Solitary Fibrous Tumor. Predicted reactivity: Mouse (80%), Rat (80%), Pig (90%), Rhesus Monkey (96%), Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STAT6
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.22 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene STAT6
Gene Accession No. P42226
Gene Alias 12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Gene Symbols STAT6
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human STAT6. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6778
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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