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Enzo Life Sciences Stattic (50mg). CAS: 19983-44-9

Supplier: Enzo Life Sciences BMLEI3680050

Small molecule STAT3-specific inhibitor which blocks activation, dimerization and nuclear translocation via binding to the STAT3 SH2 domain. It is a very useful tool for exploring STAT3-mediated signaling pathways. It blocks LPS-mediated STAT3 tyrosine phosphorylation which leads to inhibition of LPS-mediated IL-1β and IL-6 production. In primary cultures of rat neural stem cells it blocks IL-15-induced differentiation. Alternative name: 6-Nitro[b]thiophene-1,1-dioxide. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (>25 mg/ml), 100% ethanol (10 mg/ml). Long Term Storage: Ambient.
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