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Invitrogen™ Staufen Polyclonal Antibody
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Catalog No. PIPA583984
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PIPA583984 100 μL
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Catalog No. PIPA583984 Supplier Invitrogen™ Supplier No. PA583984
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TRPSEQLDYL SRVQGFQVEY KDFPKNNKNE FVSLINCSSQ PPLISHGIGK DVESCHDMAA LNILKLLSEL DQQSTEMPRT GNGPMSVCG Highest antigen sequence indentity to the following orthologs: Mouse - 93%, Rat - 93%.

STAU1 is a member of a family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human STAU1 also contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. STAU1 has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER. STAU1 is also known to interact with influenza ribonucleoproteins NS1, NP, and PA and is required for efficient viral replication.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Staufen
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Stau1
Gene Accession No. O95793
Gene Alias 5830401L18Rik; AW549911; C85792; Double-stranded RNA-binding protein Staufen homolog 1; PPP1R150; protein phosphatase 1, regulatory subunit 150; RP3-470L14.2; STAU; Stau1; staufen (RNA binding protein) homolog 1 (Drosophila); staufen double-stranded RNA binding protein 1; staufen RNA binding protein homolog 1; staufen, RNA binding protein, homolog 1
Gene Symbols Stau1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human STAU1. Recombinant protein control fragment (Product #RP-103061).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6780
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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