Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Unclassified Organic Compounds
  6. STF 083010, Tocris Bioscience™

STF 083010, Tocris Bioscience™

Catalog No. 450950
Change view
Click to view available options
Quantity:
10 mg
50 mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
45-095-0 50 mg
45-091-0 10 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Catalog No. 45-095-0 Supplier R&D Systems Supplier No. 4509/50
This item is not returnable. View return policy

Description

Inhibits IRE1α endonuclease activity

Inhibitor of IRE1α endonuclease activity; blocks endogenous XBP1 mRNA splicing. Displays cytostatic and cytotoxic effects in CD138+ multiple myeloma (MM) cells in vitro; inhibits bortezomib-induced XBP1 activity in myeloma xenografts in vivo. Does not alter IRE1α kinase activity.

Chemical Identifiers

CAS 307543-71-1
Molecular Formula C15H11NO3S2
Molecular Weight (g/mol) 317.377
InChI Key AUXKGDNZANYAPX-RAXLEYEMSA-N
Synonym regid_for_cid_6537512, stf hplc, n-2-hydroxy-1-naphthyl methylene-2-thiophenesulfonamide, e-n-2-hydroxynaphthalen-1-yl methylene thiophene-2-sulfonamide, n-z-2-oxonaphthalen-1-ylidene methyl thiophene-2-sulfonamide
PubChem CID 6537512
IUPAC Name N-[(Z)-(2-oxonaphthalen-1-ylidene)methyl]thiophene-2-sulfonamide
SMILES C1=CC=C2C(=C1)C=CC(=O)C2=CNS(=O)(=O)C3=CC=CS3

Specifications

Quantity 50 mg
Formula Weight 317.38
Percent Purity >98%
Chemical Name or Material STF 083010

Safety and Handling

Recommended Storage Store at -20°C
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.