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STING Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
$245.50 - $530.00
Specifications
| Antigen | STING |
|---|---|
| Concentration | 0.5 mg/mL |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|
PIPA5121846
|
Invitrogen™
PA5121846 |
20 μL |
Each for $245.50
|
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PIPA5121845
|
Invitrogen™
PA5121845 |
100 μL |
Each for $530.00
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Description
STING is a 379 amino acid containing signaling protein that acts as an important component of innate immune signaling. This signaling protein is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. STING may have translocon function, the translocon possibly being able to influence the induction of type I interferons and is also involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II) thus facilitating the detection of intracellular viral RNA species as well as B-form DNA and mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway. Generally seen in endoplasmic reticulum membrane, cell membrane and mitochondrion outer membrane, it is ubiquitously expressed in most of tissues.Specifications
| STING | |
| Western Blot | |
| Unconjugated | |
| Rabbit | |
| Human | |
| Q86WV6 | |
| 340061 | |
| Recombinant TMEM173 (Leu159-Pro373) expressed in E.coli. | |
| Primary | |
| -20°C | |
| TMEM173 |
| 0.5 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.05% ProClin 300 | |
| 2610307O08Rik; endoplasmic reticulum IFN stimulator; endoplasmic reticulum interferon stimulator; ERIS; hMITA; hSTING; hypothetical LOC533661; mediator of IRF3 activation; Mita; mitochondrial mediator of IRF3 activation; mitochondrial transmembrane protein 173; MMITA; Mpys; mSTING; NET23; N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner; poSTING; RGD1562552; rSTING; SAVI; Stimulator of interferon genes protein; stimulator of interferon response cGAMP interactor 1; STING; STING1; tm173; Tmem173; Transmembrane protein 173 | |
| TMEM173 | |
| IgG | |
| Antigen Affinity Chromatography | |
| Antibody |
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