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Invitrogen™ STOML1 Polyclonal Antibody
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Catalog No. PIPA521557
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PIPA521557 100 μL
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Catalog No. PIPA521557 Supplier Invitrogen™ Supplier No. PA521557
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: Molt-4. Predicted reactivity: Mouse (84%), Rat (83%), Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Stomatin-like protein 1 (STOML1) is encoded by the STOML1 gene located on chromosome 17 in humans. It is part of a family of five mammalian genes that encode peripheral membrane proteins involved in modulating ion channel functions. STOML1 is known to interact specifically with members of the acid-sensing ion channel (ASIC) family, influencing their proton sensitivity. These interactions help regulate ion transport and signaling pathways, which are critical for cellular homeostasis. In addition, STOML1 has been studied in the context of oral squamous cell carcinoma (OSCC), where it is often overexpressed along with STOML2, potentially affecting cancer progression. Structurally, STOML1 contains a stomatin domain which is crucial for its role in membrane association and ion channel modulation. Its expression in olfactory sensory neurons (OSNs) is comparatively lower than other family members, but it still contributes to the localization and functional integrity of related proteins in these cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STOML1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene STOML1
Gene Accession No. Q9UBI4
Gene Alias 1810015E19Rik; AI847431; EPB72-like 1; EPB72-like protein 1; hUNC-24; MSTP019; Protein unc-24 homolog; RGD1559463; SLP1; SLP-1; stomatin (EBP72)-like 1; stomatin (EPB72)-like 1; stomatin like 1; stomatin-like 1; stomatin-like protein 1; Stomatin-related protein; STOML1; STORP; UNC24; WPB72
Gene Symbols STOML1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human STOML1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9399
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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