Invitrogen™ SUFU Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA519555

Catalog No. PIPA519555

Description

This antibody is predicted to react with rat, chicken and dog based on sequence homology.

The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: SUFU
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SUFU
• Gene Alias: OTTHUMP00000020377; OTTHUMP00000020378; OTTHUMP00000020379; PRO1280; RP11-47A8.1; Su(fu); Sufu; SUFU negative regulator of hedgehog signaling; SUFUH; SUFUXL; suppressor of fused homolog; suppressor of fused homolog (Drosophila); UNQ650/PRO1280
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 24069, 51684
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 1% BSA and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9UMX1, Q9Z0P7
• Gene Symbols: SUFU
• Immunogen: Synthetic peptide conjugated to KLH derived from within residues 450 to the C-terminus of Human Suppressor of Fused.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG