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  6. Thermo Scientific™ Sulfo-NHS (N-hydroxysulfosuccinimide), No-Weigh™ Format 

Thermo Scientific™ Sulfo-NHS (N-hydroxysulfosuccinimide), No-Weigh™ Format
GSA_VA

Catalog No. PI24510
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10 x 2 mg
500 mg
5 g
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PI24510 500 mg
PIA39269 10 x 2 mg
PI24525 5 g
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Catalog No. PI24510 Supplier Thermo Scientific™ Supplier No. 24510
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Description

Prepare amine-reactive sulfo-NHS-ester crosslinkers or enhance carbodiimide (EDC) conjugation for peptides or proteins using N-hydroxysulfosuccinimide, CAS 106627-54-7.

Thermo Scientific™ Pierce Sulfo-NHS is pure N-hydroxysulfosuccinimide, the essential compound needed to prepare water-soluble, amine-reactive NHS-ester crosslinkers or to enhance conjugation efficiencies when using the carbodiimide EDC.

Highlights:

  • Forms an acyl amino ester with carboxyl groups when used with the EDC
  • Sulfo-NHS-activated molecule reacts efficiently with primary amines, resulting in stable amide bond
  • Allows for two-step EDC reactions between carboxyl- and amine-containing molecules
  • Sulfo-NHS-activated molecule can be stabilized by drying, allowing manufacture of amine-reactive probes and surfaces
  • Reactive groups: Sulfo-NHS
  • Reactive toward: amino groups (upon activation of carboxylates)

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TRUSTED_SUSTAINABILITY

Specifications

Chemical Reactivity Amine-Carboxyl
Cleavable No
Description Sulfo-NHS
Molecular Weight (g/mol) 217.13
PEGylated No
Content And Storage Upon receipt store at 4°C.
Cell Permeability No
Shipping Condition Ambient
Product Line Pierce
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Carbodiimide
Spacer Short (<10 Å)
Form Powder
Quantity 500 mg
Solubility Water
Format Standard, Single-use, Premium-grade
Water Soluble Yes
Product Type Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.

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