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Invitrogen™ SUPV3L1 Monoclonal Antibody (GT244)
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Catalog No. PIMA527784 Shop All Thermo Scientific Products
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PIMA527784 100 μL
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Catalog No. PIMA527784 Supplier Invitrogen™ Supplier No. MA527784
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Description

Mouse Monoclonal Antibody

Positive Control: HeLa, H1299, HCT116, GFP-human SUV3-transfected HeLa cells Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules (PubMed:29967381). ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen SUPV3L1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone GT244
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene SUPV3L1
Gene Accession No. Q8IYB8
Gene Alias 6330443E10Rik; ATP-dependent RNA helicase SUPV3L1, mitochondrial; Suppressor of var1 3-like protein 1; suppressor of var1, 3-like 1; suppressor of var1, 3-like 1 (S. cerevisiae); suppressor of var1, 3-like 1(SUV3); SUPV3L1; SUV3; Suv3 like RNA helicase; Suv3l1; SUV3-like helicase; SUV3-like protein 1
Gene Symbols SUPV3L1
Host Species Mouse
Immunogen Human SUPV3L1.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6832
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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