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Invitrogen™ SUV39H2 Polyclonal Antibody
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Catalog No. PIPA518115
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100 μg
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PIPA518115 100 μg
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Catalog No. PIPA518115 Supplier Invitrogen™ Supplier No. PA518115
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Description

Goat Polyclonal Antibody

This antibody is predicted to react with bovine, canine, human, mouse and porcine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.

The murine gene Suv39h2 encodes an H3 histone methyltransferase (HMTase) 59% identical in sequence to mouse Suv39h1. During embryogenesis, both proteins overlap in tissue expression, yet Suv39h2 transcripts are restricted to the testes in adult animals. Immunolocalization of the Suv39h2 protein during spermatogenesis indicates enrichment at the heterochromatin from the leptotene to the round spermatid stage. Moreover, Suv39h2 specifically accumulates with chromatin of the sex chromosomes, which undergo transcriptional silencing during the first meiotic prophase. Suv39h2 HMTase may also organize meiotic heterochromatin with the potential for epigenetic imprint to the male germline.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SUV39H2
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene SUV39H2
Gene Accession No. Q9H5I1
Gene Alias 4930507K23Rik; AA536750; D030054H19Rik; D2Ertd544e; FLJ23414; H3 K9 HMTase 2; H3-K9-HMTase 2; Histone H3-K9 methyltransferase 2; histone-lysine N-methyltransferase SUV39H2; KMT1; KMT1B; lysine N-methyltransferase 1B; RP11-2K17.2; Su; Su(var)3-9 homolog 2; suppressor of variegation 3-9 homolog 2; suppressor of variegation 3-9 homolog 2 (Drosophila); Suv39h histone methyltransferase; Suv39h2
Gene Symbols SUV39H2
Host Species Goat
Immunogen Synthetic peptide sequence (CKCGAVTCRGYLN) corresponding to the C-terminus amino acids of SUV39H2 (aa 398-410).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 364785, 79723
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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