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Suz12 Monoclonal Antibody (2AO9), Active Motif™
SDP

Catalog No. 501992923
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50-199-2923 10 μg
50-199-2922 100 μg
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Catalog No. 50-199-2923 Supplier Active Motif Supplier No. 39878
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Mouse Monoclonal Antibody

SUZ12 (polycomb protein SUZ12) is a zinc finger gene and has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. SUZ12 is also a component of the PRC2/EED-EZH2 complex which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3 leading to transcriptional repression of the affected target gene. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.

Specifications

Antigen Suz12
Applications ChIP Assay
Classification Monoclonal
Clone 2AO9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene SUZ12
Gene Accession No. Q15022
Gene Alias 2610028O16Rik; AI195385; AU016842; AW536442; ChET 9 protein; CHET9; Chromatin precipitated E2F target 9 protein; D11Ertd530e; JJAZ1; Joined to JAZF1 protein; KIAA0160; mKIAA0160; Polycomb protein Suz12; suppressor of zeste 12 homolog (Drosophila); Suppressor of zeste 12 protein homolog; SUZ12; SUZ12 polycomb repressive complex 2 subunit
Gene Symbols SUZ12
Host Species Mouse
Immunogen This Suz12 antibody was raised against a recombinant protein corresponding to full-length human Suz12.
Purification Method Protein G
Quantity 10 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23512
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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