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Invitrogen™ SUZ12 Recombinant Rabbit Monoclonal Antibody (7H26L21)

Catalog No. PI702490
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100 μg
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Catalog No. Quantity
PI702490 100 μg
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Catalog No. PI702490 Supplier Invitrogen™ Supplier No. 702490
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Bovine, Pig, Mouse Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

SUZ12 (polycomb protein SUZ12) is a zinc finger gene and has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. SUZ12 is also a component of the PRC2/EED-EZH2 complex which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3 leading to transcriptional repression of the affected target gene. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SUZ12
Applications ChIP Assay, Immunoprecipitation, Western Blot, RNA Immunoprecipitation, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 7H26L21
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene SUZ12
Gene Accession No. Q15022
Gene Alias 2610028O16Rik; AI195385; AU016842; AW536442; chET 9 protein; CHET9; chromatin precipitated E2F target 9 protein; D11Ertd530e; JJAZ1; Joined to JAZF1 protein; Kiaa0160; mKIAA0160; Polycomb protein Suz12; suppressor of zeste 12 homolog; suppressor of zeste 12 homolog (Drosophila); suppressor of zeste 12 protein homolog; Suz12; SUZ12 polycomb repressive complex 2 subunit
Gene Symbols SUZ12
Host Species Rabbit
Immunogen Protein corresponding to human SUZ12 [aa545-aa725].
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 102114791, 23512
Target Species Human, Cynomolgus Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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