Invitrogen™ SV40 Large T-Antigen Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5112036

Catalog No. PIPA5112036

Description

SV40 Large T-Antigen Polyclonal Antibody for Western Blot

The SV40 T antigen is encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition, the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the P105 product of the retinoblastoma susceptibility gene.

Specifications

• Antigen: SV40 Large T-Antigen
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: simian vacuolating virus 40; simian virus; Simian virus 40; sv40 large t antigen; sv40 virus large t antigen
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of SV40 Large T antigen (SV40 virus (strain 776)). The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG