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Invitrogen™ Synaptophysin Monoclonal Antibody (SP11)
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Catalog No. PIMA514532
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500 μL
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Catalog No. Quantity
PIMA514532 500 μL
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Catalog No. PIMA514532 Supplier Invitrogen™ Supplier No. MA514532
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Description

Rabbit Monoclonal Antibody

MA5-14532 targets Synaptophysin in IHC (P) and WB applications and shows reactivity with Human samples. The MA5-14532 immunogen is a synthetic peptide of human synaptophysin.

Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis. It is also involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.
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Specifications

Antigen Synaptophysin
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone SP11
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Tissue culture supernatant, TBS with 1% BSA and 0.1% sodium azide; pH 7.5
Gene Syp
Gene Accession No. P07825, P08247, Q62277
Gene Alias A230093K24Rik; AI848995; BM89 antigen; I79_012252; Major synaptic vesicle protein p38; MRX96; MRXSYP; p38; Syn; Synaptophysin; Syp; Syp I; Syp1
Gene Symbols Syp
Host Species Rabbit
Immunogen A synthetic peptide of human synaptophysin (aa 250-313).
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20977, 24804, 6855
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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