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Description
MA1-213 has been successfully used in western blot, imunofluorescence, immunohistochemistry, flow cytometry, immunoprecipitation and ELISA. MA1-213 detects Synaptophysin in human, bovine, mouse and rat samples.
Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis. It is also involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.
Specifications
Specifications
| Antigen | Synaptophysin |
| Applications | Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Monoclonal |
| Clone | SY38 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.05% sodium azide |
| Gene | Syp |
| Gene Accession No. | P07825, P08247, P20488, Q62277 |
| Gene Alias | A230093K24Rik; AI848995; BM89 antigen; I79_012252; Major synaptic vesicle protein p38; MRX96; MRXSYP; p38; Syn; Synaptophysin; Syp; Syp I; Syp1 |
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Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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