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Invitrogen™ SYNPO Polyclonal Antibody
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Catalog No. PIPA521062
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100 μg
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Catalog No. Quantity
PIPA521062 100 μg
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Catalog No. PIPA521062 Supplier Invitrogen™ Supplier No. PA521062
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Description

Rabbit Polyclonal Antibody

A suggested positive control is rat brain tissue lysate. PA5-21062 can be used with blocking peptide PEP-1176.

SYNPO (Synaptopodin) is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.
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Specifications

Antigen SYNPO
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene SYNPO
Gene Accession No. Q8CC35, Q8N3V7, Q9Z327
Gene Alias 9030217H17Rik; 9130229N11; 9330140I15Rik; AW046661; KIAA1029; Synaptopodin; SYNPO
Gene Symbols SYNPO
Host Species Rabbit
Immunogen A 17 amino acid peptide near the carboxy terminus of human SYNPO.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 104027, 11346, 60324
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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