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Invitrogen™ SYNPO2L Polyclonal Antibody
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Catalog No. PIPA596246
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100 μL
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PIPA596246 100 μL
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Catalog No. PIPA596246 Supplier Invitrogen™ Supplier No. PA596246
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: HVTPKTPPPM APKTPPPMTP KTPPPVAPKP PSRGLLDGLV NGAASSAGIP EPPRLQGRGG ELFAKRQSRA DRYVVEGTPG PGLGPRPRSP SPTPSLPPSW K; Positive Samples: Mouse heart; Cellular Location: Cytoplasm, cytoskeleton.

SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SYNPO2L
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.03 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene SYNPO2L
Gene Accession No. Q8BWB1
Gene Alias 1110054M18Rik; Chap; RGD1565434; synaptopodin 2 like; synaptopodin 2-like; synaptopodin 2-like protein; SYNPO2L
Gene Symbols SYNPO2L
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 700-800 of human SYNPO2L (NP_0011076051).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 68760
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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