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Tocris Bioscience™ T 3364366
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Catalog No. 610650
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61-065-0 50 mg
61-061-0 10 mg
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Catalog No. 61-065-0 Supplier Tocris Bioscience™ Supplier No. 6106/50
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Description

Potent and reversible fatty acid desaturase 1 inhibitor; orally bioavailable

T 3364366 is a potent and reversible fatty acid desaturase 1 (FADS1; Δ5 desaturase) inhibitor (IC50 values are 1.9 nM and 2.1 nM in human and rat hepatocyte cell lines, respectively). Exhibits >300 fold selectivity for FADS1 over FADS2 (Δ6 desaturase). Inhibits arachidonic acid production in rat and human hepatocyte cell lines. Orally bioavailable.

Specifications

Chemical Name or Material N-[2-[[3,4-Dihydro-4-oxo-3-[4-(2,2,2-trifluoroethoxy)phenyl]thieno[3,4-d]pyrimidin-2-yl]thio]ethyl]acetamide
CAS 1356354-09-0
Quantity 50 mg
Molecular Formula C18H16F3N3O3S2
Formula Weight 443.46
Purity 98%
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