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TACC3 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501562959
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50-156-2959 100 μL
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Catalog No. 50-156-2959 Supplier Bethyl Laboratories, Inc Supplier No. A302587A
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.

Specifications

Antigen TACC3
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/ml
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene TACC3
Gene Accession No. Q9Y6A5
Gene Alias Transforming acidic coiled-coil-containing protein 3, ERIC-1, TACC3, ERIC1
Gene Symbols TACC3
Host Species Rabbit
Immunogen Between 375 and 425
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10460
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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