TACC3 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-5029	150 μL

Catalog No. 50-173-5029 Supplier Proteintech Group Inc Supplier No. 256971AP150UL

Description

Rabbit Polyclonal Antibody

This antibody works well in WB, IHC and IF application.

TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.

Specifications

• Antigen: TACC3
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.27 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: TACC3
• Gene Accession No.: Q9Y6A5
• Gene Alias: ERIC 1, ERIC1, TACC3
• Gene Symbols: TACC3
• Host Species: Rabbit
• Immunogen: TACC3 Fusion Protein Ag22516
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10460
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG