Invitrogen™ TACR1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA3301

Catalog No. APS301

Description

PA3-301 detects neurokinin-1 receptor in human samples. PA3-301 has been successfully used in Western blot and immunohistochemistry (paraffin) procedures. The PA3-301 immunogen is a synthetic peptide corresponding to residues S(387) S R S D S K T M T E S F S F S S N V L S(407) of human NK1 receptor protein.

Tachykinin Receptor 1, a member of the Tachykinin Receptor subfamily, is involved in the mediation of phosphatidylinositol metabolism by the tachykinin substance P, also referred to as neurokinin 1. It is associated with the management of depression, anxiety, and stress. It is also involved in regulating behavioral responses, neuronal survival, and cardiovascular and respiratory functions. The tachykinin receptor 1 is implicated in the progression of rheumatoid arthritis and osteoarthritis. Two variants of the tachykinin receptor 1 are produced by alternative splicing. Tachykinin receptor 1 has been reported primarily in brain, and in blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries.

Specifications

• Antigen: TACR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Tacr1
• Gene Alias: neurokinin 1 receptor; neurokinin receptor 1; neurokinin receptor subtype NK1; neurokinin-1 receptor; Nk1 receptor; NK-1 receptor; Nk1r; NK-1R; NKIR; SPR; substance p receptor; substance-P receptor; TAC1R; tachykinin receptor 1; tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor); TACR1; truncated neurokinin-1 receptor
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: Conc. Not Determined
• Formulation: whole serum with 0.05% sodium azide
• Gene Accession No.: P25103
• Gene Symbols: Tacr1
• Immunogen: Synthetic peptide corresponding to residues S(387) S R S D S K T M T E S F S F S S N V L S(407) of human NK1 receptor protein.
• Regulatory Status: RUO
• Gene ID (Entrez): 6869
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid