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TACR3 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501733832 Shop All Proteintech Group Inc Products
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50-173-3832 150 μL
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Catalog No. 50-173-3832 Supplier Proteintech Group Inc Supplier No. 223341AP150UL
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Rabbit Polyclonal Antibody

Substance P (SP) and neurokinin-A (NK-A) are members of the tachykinins, and they function as modulators of the immune and hematopoietic systems. The tachykinins interact with each of three cloned neurokinin (NK) receptors (NK-1R, NK-2R, NK-3R), with SP and NK-A exhibiting binding preferences for NK-1R and NK-2R, respectively. NK-4R shares close homology with NK-3R, and both have nearly identical pharmacologicl properties. In the normal ileum and colon, NK-1R and NK-2R are localized to smooth muscle cells of the muscularis mucosae and propria and to a few inflammatory cells of the lamina propria. NK-1R expression is also found in the muscular wall of submucosal blood vessels, enteric neurons and, to a lesser degree, in surface epithelial cells. NK-3R is found in the spinal cord in both lamina X and lamina II.

Specifications

Antigen TACR3
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.17 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TACR3
Gene Accession No. P29371
Gene Alias Neurokinin B receptor, Neuromedin K receptor, NK 3 receptor, NK 3R, NK3R, NKR, TAC3R, TAC3RL, tachykinin receptor 3, TACR3
Gene Symbols TACR3
Host Species Rabbit
Immunogen TACR3 Fusion Protein Ag17808
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6870
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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