Invitrogen™ TADA2L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA567425

Catalog No. PIPA567425

Description

Immunogen sequence: MDRLGPFSNDP SDKPPCRGCS SYLMEPYIKC AECGPPPFFL CLQCFTRGFE YKKHQSDHTY EIMTSD Highest antigen sequence identity to the following orthologs - mouse 97%, rat 99%.

TADA2L (transcriptional adapter 2-like), also known as TADA2A (transcriptional adapter 2-alpha) or ADA2-like protein, is a 443 amino acid nuclear protein that exists as 2 alternatively spliced isoforms. While most abundantly expressed in testis, TADA2L is present in all tissues. TADA2L contains one SANT domain and one SWIRM domain, and interacts with GCN5 and GR (NR3C1). Its ability to bind double-stranded DNA allows TADA2L to play a role in chromatin remodeling. Although it makes up part of the PCAF complex, TADA2L is also a component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. The gene that encodes TADA2L contains 71,408 bases and maps to human chromosome 17q12. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to osteogenesis imperfecta, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome.

Specifications

• Antigen: TADA2L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TADA2A
• Gene Alias: ADA2; ADA2A; ADA2-like protein; AV319371; D030022J10Rik; hADA2; KL04P; TADA2A; TADA2L; transcriptional adapter 2-alpha; Transcriptional adapter 2-like; transcriptional adaptor 2 alpha; transcriptional adaptor 2A
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6871
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O75478
• Gene Symbols: TADA2A
• Immunogen: Recombinant Human TADA2L. Recombinant protein control fragment (Product #RP-108086).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG