Invitrogen™ TAF10 Monoclonal Antibody (23TA-1H8)

Catalog No.	Quantity
PIMA3069	50 μL

Catalog No. PIMA3069 Supplier Invitrogen™ Supplier No. MA3069

Description

Mouse Monoclonal Antibody

MA3-069 detects TAF10 from human, rat, and non-human primate samples. MA3-069 does not detect the TAF10 in mouse samples MA3-069 has been successfully used in Western blot, immunofluorescence and flow cytometry applications. The MA3-069 immunogen is the synthetic peptide coupled to ovalalbumin aa 1 to aa 20.

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs.

Specifications

• Antigen: TAF10
• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: 23TA-1H8
• Concentration: Conc. Not Determined
• Conjugate: Unconjugated
• Formulation: ascites with 0.05% sodium azide
• Gene: TAF10
• Gene Accession No.: Q12962
• Gene Alias: 30kDa; AU041226; im:6899389; mTAFII30; si:dkey-72l14.8; STAF28; TAF(II)30; TAF10; TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30 kDa; TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa; TAF2A; Taf2h; TAFII30; TAFII-30; TATA box binding protein (TBP)-associated factor, RNA polymerase II, H, 30 kDa; TATA box binding protein (TBP)-associated factor, RNA polymerase II, H, 30kD; TATA box binding protein associated factor 10; TATA-box binding protein associated factor 10; TBP-related factor 10; transcription initiation factor TFIID 30 kD subunit; transcription initiation factor TFIID 30 kDa subunit; Transcription initiation factor TFIID subunit 10
• Gene Symbols: TAF10
• Host Species: Mouse
• Immunogen: Synthetic peptide coupled to ovalalbumin aa 1 to 20.
• Quantity: 50 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 293345, 6881
• Target Species: Human, Rat, Monkey
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ