Invitrogen™ TAF4 Monoclonal Antibody (20TA-1B12)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA3075

Catalog No. PIMA3075

Description

MA3-075 detects TATA-Binding Protein (TBP) Associated factor 4 from human and mouse samples. MA3-075 has been successfully used in Western blot and immunofluorescence applications. The MA3-075 immunogen is a recombinant TAF4 protein. Epitope is localized between aa 815 and 836.

TAF II p105, also called TAF4B, is a celltype specific transcriptional co-activator that is a component of the TFIID complex. Expressed primarily in B cells and ovarian granulosa cells, TAF II p105 can interact with OCBA/POU2AF1 to activate B cell-specific octamerdependent transcription. Additionally, TAF II p105 plays an important role in co-activating the transcription factor NFkB and is essential for activation of anti-apoptotic genes such as TNFAIP3. TAF II p135, also known as TAF4, TAF2C, TAF2C1, TAF4A or TAFII130, is a 1,085 amino acid subunit of TFIID that accelerates transcriptional activation triggered by thyroid hormone (TR) or retinoic acid (RA). Localized to the nucleus, TAF II p135 contains one TAFH domain and is thought to bind to proteins that contain glutamine-rich domains, such as the transcription factor CREB.

Specifications

• Antigen: TAF4
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Ascites with 0.05% sodium azide
• Gene Accession No.: O00268
• Gene Symbols: TAF4
• Immunogen: Recombinant TAF4 protein. Epitope is localized between aa 815 and 836.
• Regulatory Status: RUO
• Gene ID (Entrez): 228980, 6874
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Clone: 20TA-1B12
• Conjugate: Unconjugated
• Gene: TAF4
• Gene Alias: 135kDa; AI450312; FLJ41943; LOW QUALITY PROTEIN: transcription initiation factor TFIID subunit 4; RNA polymerase II TBP-associated factor subunit C; TAF(II)130; TAF(II)135; TAF2C; TAF2C1; TAF4; TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa; Taf4a; TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135 kD; TAFII 130; TAFII 135; TAFII130; TAFII-130; TAFII135; TAFII-135; TATA box binding protein (TBP)-associated factor, RNA polymerase II, C1, 130kD; TATA box binding protein associated factor 4; TATA-box binding protein associated factor 4; TBP-associated factor 4; Transcription initiation factor TFIID 130 kDa subunit; transcription initiation factor TFIID 135 kD subunit; transcription initiation factor TFIID 135 kDa subunit; Transcription initiation factor TFIID subunit 4
• Host Species: Mouse
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1 κ