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Invitrogen™ TAF4 Monoclonal Antibody (20TA-1B12)
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Catalog No. PIMA3075
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PIMA3075 50 μL
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Catalog No. PIMA3075 Supplier Invitrogen™ Supplier No. MA3075
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Mouse Monoclonal Antibody

MA3-075 detects TATA-Binding Protein (TBP) Associated factor 4 from human and mouse samples. MA3-075 has been successfully used in Western blot and immunofluorescence applications. The MA3-075 immunogen is a recombinant TAF4 protein. Epitope is localized between aa 815 and 836.

TAF II p105, also called TAF4B, is a celltype specific transcriptional co-activator that is a component of the TFIID complex. Expressed primarily in B cells and ovarian granulosa cells, TAF II p105 can interact with OCBA/POU2AF1 to activate B cell-specific octamerdependent transcription. Additionally, TAF II p105 plays an important role in co-activating the transcription factor NFkB and is essential for activation of anti-apoptotic genes such as TNFAIP3. TAF II p135, also known as TAF4, TAF2C, TAF2C1, TAF4A or TAFII130, is a 1,085 amino acid subunit of TFIID that accelerates transcriptional activation triggered by thyroid hormone (TR) or retinoic acid (RA). Localized to the nucleus, TAF II p135 contains one TAFH domain and is thought to bind to proteins that contain glutamine-rich domains, such as the transcription factor CREB.
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Specifications

Antigen TAF4
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 20TA-1B12
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.05% sodium azide
Gene TAF4
Gene Accession No. O00268
Gene Alias 135kDa; AI450312; FLJ41943; LOW QUALITY PROTEIN: transcription initiation factor TFIID subunit 4; RNA polymerase II TBP-associated factor subunit C; TAF(II)130; TAF(II)135; TAF2C; TAF2C1; TAF4; TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa; Taf4a; TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor; TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135 kD; TAFII 130; TAFII 135; TAFII130; TAFII-130; TAFII135; TAFII-135; TATA box binding protein (TBP)-associated factor, RNA polymerase II, C1, 130kD; TATA box binding protein associated factor 4; TATA-box binding protein associated factor 4; TBP-associated factor 4; Transcription initiation factor TFIID 130 kDa subunit; transcription initiation factor TFIID 135 kD subunit; transcription initiation factor TFIID 135 kDa subunit; Transcription initiation factor TFIID subunit 4
Gene Symbols TAF4
Host Species Mouse
Immunogen Recombinant TAF4 protein. Epitope is localized between aa 815 and 836.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 228980, 6874
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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