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Invitrogen™ Talin 1 Polyclonal Antibody
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Catalog No. PIPA580133
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100 μg
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PIPA580133 100 μg
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Catalog No. PIPA580133 Supplier Invitrogen™ Supplier No. PA580133
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Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human HepG2 whole cell, human Jurkat whole cell, rat C6 whole cell, mouse NIH/3T3 whole cell. IHC: human Lung cancer tissue, mouse small intestine tissue, human intestinal cancer tissue, human tonsil tissue, rat small intestine tissue, rat lung tissue, rat spleen tissue, mouse spleen tissue.

Talin, a multifunctional constituent of cell-substratum attachment sites, is a high molecular weight protein (225-235 kDa) found in variety of tissues and cell types. It is localized at a subset of adherens junctions, specialized cell-cell and cell-matrix associations that are characterized by the presence of filamentous actin at the cytoplasmic face of the junctional complex. In cultured cells, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin. Talin interacts with at least two other proteins that are localized at adhesion plaques, vinculin and integrin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Talin 1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene TLN1
Gene Accession No. P26039, Q9Y490
Gene Alias ILWEQ; KIAA1027; talin 1; talin-1; TLN; TLN1
Gene Symbols TLN1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence of human Talin 1 (QQLAPREGISQEALHTQMLTAVQEISHLIEPLANAARAEASQ).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21894, 313494, 7094
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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