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Invitrogen™ TARC Recombinant Rabbit Monoclonal Antibody (B22H33L5)

Catalog No. PI700655
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100 μg
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PI700655 100 μg
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Catalog No. PI700655 Supplier Invitrogen™ Supplier No. 700655
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Description

Rabbit Recombinant Monoclonal Antibody

Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

TARC ligand (CCL17) belongs to the CC chemokine family. It is a small cytokine and the gene is located on q arm of chromosome 16, in humans, along with other chemokines. TARC specifically binds to T-cells and interacts with chemokine receptors CCR4 and CCR8. It plays an important role in T cell development in thymus as well as in trafficking and activation of mature T cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TARC
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone B22H33L5
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Gene CCL17
Gene Accession No. Q92583
Gene Alias A-152E5.3; ABCD-2; CC chemokine TARC; C-C motif chemokine; C-C motif chemokine 17; C-C motif chemokine ligand 17; CCL17; chemokine (C-C motif) ligand 17; SCYA17; Scya17l; small inducible cytokine subfamily A (Cys-Cys), member 17; small inducible cytokine subfamily A17; small-inducible cytokine A17; T cell-directed CC chemokine; TARC; Thymus and activation-regulated chemokine
Gene Symbols CCL17
Host Species Rabbit
Immunogen A portion of recombinant human TARC protein corresponding to amino acids 24-94.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20295, 6361
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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