Invitrogen™ TARC Recombinant Rabbit Monoclonal Antibody (B22H33L5)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ 700655

Catalog No. PI700655

Description

Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

TARC ligand (CCL17) belongs to the CC chemokine family. It is a small cytokine and the gene is located on q arm of chromosome 16, in humans, along with other chemokines. TARC specifically binds to T-cells and interacts with chemokine receptors CCR4 and CCR8. It plays an important role in T cell development in thymus as well as in trafficking and activation of mature T cells.

Specifications

• Antigen: TARC
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide
• Gene Accession No.: Q92583
• Gene Symbols: CCL17
• Immunogen: A portion of recombinant human TARC protein corresponding to amino acids 24-94.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: B22H33L5
• Conjugate: Unconjugated
• Gene: CCL17
• Gene Alias: A-152E5.3; ABCD-2; CC chemokine TARC; C-C motif chemokine; C-C motif chemokine 17; C-C motif chemokine ligand 17; CCL17; chemokine (C-C motif) ligand 17; SCYA17; Scya17l; small inducible cytokine subfamily A (Cys-Cys), member 17; small inducible cytokine subfamily A17; small-inducible cytokine A17; T cell-directed CC chemokine; TARC; Thymus and activation-regulated chemokine
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 20295, 6361
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid