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Tocris Bioscience™ Taxol
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Catalog No. 109710
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10-971-0 10 mg
10-975-0 50 mg
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Description

Promotes assembly and inhibits disassembly of microtubules

Taxol, also known as paclitaxel, promotes and stabilizes tubulin polymerization, causing cell cycle arrest. In CCRF-HSB-2 cells, Taxol induces autocatalytic activation of caspase-10, triggering apoptosis. Taxol is an antitumor agent. In a mouse model of bladder cancer Taxol decreases tumor growth. Taxol also prolongs survival of mice transplanted with human ovarian carcinoma xenografts. Taxol improves neurological outcome and magnetic resonance imaging biomarkers after traumatic brain injury in mice.

Identifiants chimiques

CAS 33069-62-4
Molecular Formula C47H51NO14

Spécifications

Quantity 10 mg
Formula Weight 853.92
Purity >99%
Molecular Weight (g/mol) 853.92
Chemical Name or Material Taxol

Sécurité et manipulation

Recommended Storage Store at +4°C
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