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TARGETMOL CHEMICALS INC TAK-243 10MG
SDP

Supplier:  TARGETMOL CHEMICALS INC T1697410MG

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Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. TAK-243 (MLN7243) is a small molecule inhibitor of ubiquitin-activating enzyme (UAE IC50=1 nM) which blocks ubiquitin conjugation disrupting monoubiquitin signaling as well as global protein ubiquitination. TAK-243 (MLN7243) induces endoplasmic reticulum (ER) stress abrogates NF-(kappa)B pathway activation and promotes apoptosiswith potential antineoplastic activity. purity: 98%

Catalog No. 50-258-1133


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