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  6. TBC1D17 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech 

TBC1D17 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. 501732914 Shop All Proteintech Group Inc Products
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50-173-2914 150 μL
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Catalog No. 50-173-2914 Supplier Proteintech Group Inc Supplier No. 204821AP150UL
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Description

Rabbit Polyclonal Antibody

Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR) and reduces Rab8 recruitment to tubules emanating from the endocytic recycling compartment (ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50; the function requires its catalytic activity, however, the involved Rab is not known.

Specifications

Antigen TBC1D17
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.45 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TBC1D17
Gene Accession No. Q8BYH7, Q9HA65
Gene Alias TBC1 domain family member 17, TBC1 domain family, member 17, TBC1D17
Gene Symbols TBC1D17
Host Species Rabbit
Immunogen TBC1D17 Fusion Protein Ag14358
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 233204, 292886, 79735
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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