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Invitrogen™ TBL1X/TBL1XR1 Polyclonal Antibody
Goat Polyclonal Antibody
Supplier: Invitrogen™ PA19108
Description
This antibody is expected to recognize the human protein TBL1XR1 (NP_078941) as well as TBL1X. Variants (NP_005638.1; NP_001132938.1) encode isoform a (TBL1X) and variants (NP_001132939.1; NP_001132940.1 ) encode isoform b (TBL1X). This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.
Specifications
TBL1X/TBL1XR1 | |
Polyclonal | |
Unconjugated | |
TBL1X | |
5330429M20; 8030499H02Rik; A630076E03Rik; AW539987; C21; C230089I12Rik; DC42; EBI; F-box-like/WD repeat protein TBL1XR1; F-box-like/WD repeat-containing protein TBL1X; F-box-like/WD repeat-containing protein TBL1XR1; Ira1; MRD41; nuclear receptor co-repressor/HDAC3 complex subunit; nuclear receptor corepressor/HDAC3 complex subunit TBLR1; SMAP55; TBL1; TBL1-related protein 1; Tbl1x; Tbl1xr1; TBLR1; transducin (beta)-like 1 X-linked; transducin (beta)-like 1 X-linked receptor 1; transducin (beta)-like 1X-linked; transducin (beta)-like 1X-linked receptor 1; transducin beta-like 1X-related protein 1; Transducin beta-like protein 1X; transducin-beta-like protein 1, X-linked | |
Goat | |
Ammonium sulfate precipitation | |
RUO | |
6907, 79718 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Immunohistochemistry (Paraffin) | |
0.5 mg/mL | |
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
O60907, Q9BZK7 | |
TBL1X, Tbl1xr1 | |
Synthetic peptide corresponding to the C terminus amino acids SASDGSVCVLDLRK (aa 564-577). | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |
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