Invitrogen™ TBL1Y Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550884

Catalog No. PA550884

Description

The antibody detects endogenous levels of total TBL1 protein.

The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.

Specifications

• Antigen: TBL1Y
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TBL1Y
• Gene Alias: F-box-like/WD repeat-containing protein TBL1Y; TBL1; TBL1Y; transducin (beta)-like 1, Y-linked; transducin beta-like 1; transducin beta-like protein 1Y; Transducin-beta-like protein 1, Y-linked
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 90665
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q9BQ87
• Gene Symbols: TBL1Y
• Immunogen: Fusion protein of human transducin (beta)-like 1, Y-linked.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG