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Invitrogen™ TBL1Y Polyclonal Antibody
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Catalog No. PA550884
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100 μL
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PA550884 100 μL
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Catalog No. PA550884 Supplier Invitrogen™ Supplier No. PA550884
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total TBL1 protein.

The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TBL1Y
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene TBL1Y
Gene Accession No. Q9BQ87
Gene Alias F-box-like/WD repeat-containing protein TBL1Y; TBL1; TBL1Y; transducin (beta)-like 1, Y-linked; transducin beta-like 1; transducin beta-like protein 1Y; Transducin-beta-like protein 1, Y-linked
Gene Symbols TBL1Y
Host Species Rabbit
Immunogen Fusion protein of human transducin (beta)-like 1, Y-linked.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 90665
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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