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Invitrogen™ TBX1 Polyclonal Antibody
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Catalog No. PIPA540712
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100 μL
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PIPA540712 100 μL
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Catalog No. PIPA540712 Supplier Invitrogen™ Supplier No. PA540712
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Description

Rabbit Polyclonal Antibody

Peptide sequence: PNPELRLEAP GASEPLHHHP YKYPAAAYDH YLGAKSRPAP YPLPGLRGHG Sequence homology: Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%.

TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TBX1
Applications Immunohistochemistry, Western Blot, Immunocytochemistry, Surface Plasmon Resonance
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene TBX1
Gene Accession No. O43435
Gene Alias brachyury; CAFS; CATCH22; CTHM; DGCR; DGS; DORV; LOW QUALITY PROTEIN: T-box transcription factor TBX1; T-box 1; T-box 1 transcription factor C; T-box protein 1; T-box transcription factor 1; T-box transcription factor TBX1; T-box transcription factor TBX1; LOW QUALITY PROTEIN: T-box transcription factor TBX1; Tbx1; TBX1C; Testis-specific T-box protein; TGA; VCF; VCFS
Gene Symbols TBX1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the C-terminal of human TBX1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6899
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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