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  5. Tocris Bioscience™ TC JL 37

Tocris Bioscience™ TC JL 37
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Catalog No. 612510
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61-251-0 10 mg
61-255-0 50 mg
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Catalog No. 61-251-0 Supplier Tocris Bioscience™ Supplier No. 6125/10
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Description

Potent TYK2 inhibitor

TC JL 37 is a potent inhibitor of tyrosine kinase 2 (TYK2, Ki = 1.6 nM). Shows some selectivity for TYK2 over JAK1/2/3. Inhibits IFNγ production in vivo in mice. Orally bioavailable.

Specifications

Chemical Name or Material 2-Chloro-4-cyano-6-fluoro-N-[2-[[[(1R,2R)-2-fluorocyclopropyl]carbonyl]amino]-4-pyridinyl]benzamide
CAS 1258294-34-6
Assay Percent Range >98%
Quantity 10 mg
Molecular Formula C17H11ClF2N4O2
Formula Weight Observed MW: 376.74
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