TCAP Monoclonal Antibody (OTI6C1), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-2024	100 μL

Catalog No. 50-168-2024 Supplier OriGene Supplier No. TA808277

Description

Mouse Monoclonal Antibody

Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.

Specifications

• Antigen: TCAP
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI6C1
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: TCAP
• Gene Accession No.: O15273
• Gene Alias: CMD1N, CMH25, LGMD2G, T-cap, TELE, telethonin
• Gene Symbols: TCAP
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human TCAP produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8557
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a