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Invitrogen™ TCAP Polyclonal Antibody
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Catalog No. PIPA543144
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100 μL
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PIPA543144 100 μL
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Catalog No. PIPA543144 Supplier Invitrogen™ Supplier No. PA543144
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Description

Rabbit Polyclonal Antibody

Peptide sequence: IQLQELLALE TALGGQCVDR QEVAEITKQL PPVVPVSKPG ALRRSLSRSM Sequence homology: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%.

Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TCAP
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene Tcap
Gene Accession No. O15273
Gene Alias 19 kDa sarcomeric protein; AI503981; AJ223855; CMD1N; CMH25; LGMD2G; limb girdle muscular dystrophy 2G (autosomal recessive); Tcap; T-cap; TELE; telethonin; teneurin C-terminal associated peptide; titin cap protein; titin-cap; titin-cap (telethonin)
Gene Symbols Tcap
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human TCAP.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8557
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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