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TCL1A Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. p-7088009 Shop All Proteintech Group Inc Products
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50-172-6334 150 μL
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Catalog No. 50-172-6334 Supplier Proteintech Group Inc Supplier No. 104751AP150UL
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Description

Rabbit Polyclonal Antibody

Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha or TCR-beta regulatory elements (summarized by Virgilio et al., 1998). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (Laine et al., 2000).

Specifications

Antigen TCL1A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene TCL1A
Gene Accession No. P56279
Gene Alias Oncogene TCL 1, Oncogene TCL1, Protein p14 TCL1, T cell leukemia/lymphoma 1A, TCL1, TCL1A
Gene Symbols TCL1A
Host Species Rabbit
Immunogen TCL1A Fusion Protein Ag0786
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8115
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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