Invitrogen™ TCP-1 delta Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527954

Catalog No. PIPA527954

Description

Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (97%), Rat (97%), Zebrafish (88%), Xenopus laevis (92%), Chicken (93%), Chimpanzee (99%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).

Specifications

• Antigen: TCP-1 delta
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cct4
• Gene Alias: 2610204B21Rik; A45; C78323; CCT4; cct4 protein; Cctd; CCT-delta; chaperonin containing t-complex polypeptide 1, delta subunit; chaperonin containing TCP1 subunit 4; chaperonin containing Tcp1, subunit 4 (delta); chaperonin subunit 4 (delta); SRB; Stimulator of TAR RNA-binding; T complex protein 1, delta; T-complex protein 1 subunit delta; TCP-1 delta; TCP-1-delta; Unknown (protein for MGC:134500); zgc:65789; zgc:77192
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10575
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.59 mg/mL
• Formulation: 0.1M Tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P50991
• Gene Symbols: Cct4
• Immunogen: Recombinant fragment corresponding to a region within amino acids 105 and 496 of Human TCP-1 delta.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG