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TCTN3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

$518.60

Specifications

Antigen TCTN3
Concentration 0.23 mg/mL
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-173-0701
SDP
Encompass_Preferred
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Proteintech Group Inc
160851AP150UL
150 μL
Each of 1 for $518.60
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Description

Description

TCTN3 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN3 is not known, it is 58% similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
Specifications

Specifications

TCTN3
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Rabbit
Human, Mouse
Q6NUS6, Q8R2Q6
26123, 67590
TCTN3 Fusion Protein Ag9084
Primary
-20°C
TCTN3
0.23 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
C10orf61, TCTN3, TECT3, Tectonic 3, tectonic family member 3, UNQ1881/PRO4324
Tctn3
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

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