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Invitrogen™ TDE1 Polyclonal Antibody
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Catalog No. PA549823
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100 μL
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PA549823 100 μL
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Catalog No. PA549823 Supplier Invitrogen™ Supplier No. PA549823
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Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total SERINC3 protein.

TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue. It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis. The mechanism through which TDE1 protects cells is poorly understood, but may involve aberrant methylation of TDE1 complexes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TDE1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Serinc3
Gene Accession No. Q13530, Q9QZI9
Gene Alias AA959945; AA960047; Aigp1; AIGP-1; axotomy-induced glyco/Golgi protein 1; Axotomy-induced glycoprotein 1; DIFF33; Membrane protein TMS-1; SBBI99; Serinc3; Serine incorporator 3; TDE; TDE1; Tms1; TMS-1; tumor differentially expressed 1; tumor differentially expressed protein 1
Gene Symbols Serinc3
Host Species Rabbit
Immunogen Synthesized peptide derived from C-terminal of human SERC3.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10955, 26943, 296350
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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