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Invitrogen™ TDG Monoclonal Antibody (OTI3A12)
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Catalog No. PIMA527004
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100 μL
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Catalog No. Quantity
PIMA527004 100 μL
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Catalog No. PIMA527004 Supplier Invitrogen™ Supplier No. MA527004
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Description

Mouse Monoclonal Antibody

TDG Monoclonal Antibody for IHC (P)

The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mis paired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TDG
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone OTI3A12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TDG
Gene Accession No. Q13569
Gene Alias C-JUN leucine zipper interactive protein JZA-3; E130317C12Rik; G/T mismatch-specific thymine DNA glycosylase; hTDG; Jza1; JZA-3; Tdg; thymine DNA glycosylase; thymine-DNA glycosylase
Gene Symbols TDG
Host Species Mouse
Immunogen Human recombinant protein fragment corresponding to amino acids 160-253 of TDG produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6996
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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