Learn More
TDP1 Mouse anti-Human, Clone: OTI4H1, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF503768

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.Specifications
TDP1 | |
Monoclonal | |
Unconjugated | |
TDP1 | |
tyrosyl-DNA phosphodiesterase 1 | |
Mouse | |
Affinity Chromatography | |
RUO | |
55775 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Western Blot | |
OTI4H1 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q9NUW8 | |
TDP1 | |
Full length human recombit protein of human TDP1 produced in HEK293T cell. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.