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TARGETMOL CHEMICALS INC TELOMERASE-IN-1 5MG

Supplier: TARGETMOL CHEMICALS INC T12009

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Telomerase-IN-1 is a telomerase inhibitor (IC50 0.19 uM). telomerase-IN-1 activates hTERT expression through the endoplasmic reticulum stress (ERS) of the ER overreaction (EOR) which then induces ERS leading to apoptosis. telomerase-IN-1 leads to inhibition of cell proliferation through the expression of downstream signaling molecules including Telomease-IN-1 has high inhibitory activity against telomerase high anti-proliferative capacity against SMMC-7721 cells and no significant toxic effect on human normal hepatocytes. telomerase-IN-1 in xenograft tumor model exhibited antitumor activity. purity: 97%
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