Tocris Bioscience™ Tertiapin-Q 

Selective blocker of inward-rectifier K+ channels

Manufacturer:  Tocris Bioscience™ 1316/1

Catalog No. 13-161-R

Description

A high affinity blocker for inward-rectifier K+ channels, this compound is a stable derivative of the bee venom toxin tertiapin. Binds to ROMK1 (Kir1.1) and GIRK1/4 (Kir3.1/3.4) channels with high affinity (Ki values are 1.3 and 13.3 nM respectively) and is selective over Kir2.1 channels. Derivative tertiapin LQ (Cat. No. 4339) also available.

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Specifications

• Description: Tertiapin-Q
• Quantity: 1mg
• Product Type: Tertiapin-Q

• Molecular Weight: 2452
• Sequence: Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Gln-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2 (Disulfide bridges: 3 - 14, 5 - 18)

For Research Use Only