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Tocris Bioscience™ Tertiapin-Q
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Catalog No. 13161R
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13-161-R 1 mg
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Catalog No. 13-161-R Supplier Tocris Bioscience™ Supplier No. 1316/1
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Description

Selective blocker of inward-rectifier K+ channels

Tertiapin-Q is a high affinity blocker for inward-rectifier K+ channels. Tertiapin-Q is a stable derivative of the bee venom toxin tertiapin. Tertiapin-Q binds to ROMK1 (Kir1.1) and GIRK1/4 (Kir3.1/3.4) channels with high affinity (Ki values are 1.3 and 13.3 nM respectively) and is selective over Kir2.1 channels. Tertiapin-Q improves heart rate and atrioventricular conduction in a mouse model of bradycardia. Derivative Tertiapin LQ (Cat. No. 4339) also available.

Specifications

Purity 0.95
Content And Storage Store at -20°C
Description Tertiapin-Q
Molecular Weight (g/mol) 2452
Product Type Tertiapin-Q
Quantity 1 mg
Sequence Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Gln-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2 (Disulfide bridges: 3 - 14, 5 - 18)

For Research Use Only

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