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TET3 Monoclonal Antibody (OTI3B3), TrueMAB™, OriGene
SDP

Catalog No. 501679987
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100 μL
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50-167-9987 100 μL
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Catalog No. 50-167-9987 Supplier OriGene Supplier No. TA803928
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Description

Mouse Monoclonal Antibody

TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid maligcies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.

Specifications

Antigen TET3
Applications Western Blot
Classification Monoclonal
Clone OTI3B3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene TET3
Gene Accession No. O43151
Gene Alias hCG_40738
Gene Symbols TET3
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 241-568 of human TET3 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 200424
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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