Tet3 Rabbit anti-Mouse, Unconjugated, Polyclonal, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer:  Active Motif 61396

Catalog No. 50-199-4155

Description

TET3, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine and is most abundantly expressed in hematopoietic cells. Unlike the related TET2 protein, mutations in TET3 have not been observed in any myeloid malignancies. TET3 has been shown to be involved in the demethylation of zygotic DNA before the first mitosis and has been suggested to be involved in the epigenetic reprogramming of the zygotic paternal DNA following natural fertilization and may also contribute to somatic cell nuclear reprogramming during animal cloning.

Specifications

• Antigen: Tet3
• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: TET3
• Format: Liquid
• Host Species: Rabbit
• Isotype: IgG
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Mouse

• Gene Symbol: TET3
• Concentration: Conc. Not Determined
• Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
• Gene Accession No.: Q8BG87
• Gene Alias: B430006D22Rik; BC037432; D230004J03Rik; hCG_40738; KIAA0401; Methylcytosine dioxygenase TET3; MGC22014; probable methylcytosine dioxygenase TET3; putative methylcytosine dioxygenase; Tet methylcytosine deoxygenase 3 isoform; tet methylcytosine dioxygenase 3; tet oncogene family member 3; Tet3
• Immunogen: This antibody was raised against a recombinant protein corresponding to amino acids 1159-1329 of mouse Tet3.
• Quantity: 10 μL
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Primary or Secondary: Primary
• Gene ID (Entrez): 194388