Tetracycline hydrochloride, 96%

Description

Tetracycline hydrochloride, CAS # 64-75-5, is a wide-spectrum antibiotic that targets both gram-negative and gram-positive bacteria. | CAS: 64-75-5 | C22H25ClN2O8 | 480.898 g/mol

Tetracycline hydrochloride is used to induce apoptosis in osteoclasts. It is used to treat acne and other skin infections, respiratory tract infections like pneumonia, genital, urinary infections, leptospirosis, helicobacter pylori, taxoplasmosis, mycoplasma, psittacosis for dog and cats. It also works more effectively in animals that have tick-borne infections. It is also useful in cell culture applications.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Tetracycline hydrochloride is the hydrochloride salt of the antibiotic tetracycline
• Tetracycline blocks amino acyl-tRNA binding during bacterial protein synthesis
• Tetracycline is a broad-spectrum naphthacene antibiotic that inhibits growth of both gram positive and gram negative bacteria

Applications

• Tetracycline may be used as a selection agent in cell culture
• It may also be used to activate inducible gene expression in engineered cells

Specifications

Chemical Identifiers

• CAS: 64-75-5
• Molecular Formula: C22H25ClN2O8
• Molecular Weight (g/mol): 480.898
• MDL Number: MFCD00078142
• InChI Key: HTXDZWDXSWLLLW-FMZCEJRJSA-N
• PubChem CID: 129628373
• IUPAC Name: (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,11,12a-pentahydroxy-6-methyl-1,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride
• SMILES: CC1(C2CC3C(C(=C(C(=O)C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)C(=O)N)O)N(C)C)O.Cl

• Type: Tetracycline Hydrochloride
• Melting Point: 220°C to 223°C
• Quantity: 100 g
• Optical Rotation: −247° (c=1, 0.1M HCl)
• Assay Percent Range: 0.98
• Sensitivity: Air and light sensitive
• Merck Index: 14,9196
• Solubility Information: Soluble in water,dimethyl sulfoxide,methanol and ethanol. Insoluble in ether and hydrocarbons.
• Formula Weight: 480.91
• Percent Purity: 96%
• Chemical Name or Material: Tetracycline hydrochloride

Safety and Handling

Hazard Category	H319-H361d
Hazard Statement	GHS H Statement H361-H319 Suspected of damaging fertility or the unborn child. Causes serious eye irritation.
Precautionary Statement	P201-P202-P261-P264b-P271-P280i-P281-P304+P340-P305+P351+P338-P308+P313-P501c
EINECSNumber	200-593-8
RTECSNumber	QI9100000
TSCA	Yes
Recommended Storage	Ambient temperatures; Store under Nitrogen

SDS

RUO – Research Use Only