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Invitrogen™ TFB2M Polyclonal Antibody
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Catalog No. PIPA540897
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100 μL
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PIPA540897 100 μL
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Catalog No. PIPA540897 Supplier Invitrogen™ Supplier No. PA540897
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Description

Rabbit Polyclonal Antibody

Peptide sequence: ECNPGPGILT QALLEAGAKV VALESDKTFI PHLESLGKNL DGKLRVIHCD Sequence homology: Horse: 100%; Human: 100%; Rabbit: 83%; Rat: 85%.

S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TFB2M
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene Tfb2m
Gene Accession No. Q9H5Q4
Gene Alias dimethyladenosine transferase 2, mitochondrial; FLJ22661; FLJ23182; HCV NS5A-transactivated protein 5; Hepatitis C virus NS5A-transactivated protein 5; Hkp1; h-mtTFB; h-mtTFB2; house-keeping protein 1; hTFB2M; mitochondrial 12S rRNA dimethylase 2; Mitochondrial transcription factor B2; mTFB2M; mtTFB2; NS5ATP5; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2; TFB2M; transcription factor B2, mitochondrial
Gene Symbols Tfb2m
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human TFB2M (aa 101-150).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64216
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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