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TFEB Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Catalog No. 501565746
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50-156-5746 100 μL
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Catalog No. 50-156-5746 Supplier Bethyl Laboratories, Inc Supplier No. A303673A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors. Recent studies have shown that lysosomal biogenesis is regulated by TFEB, which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1. Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes.

Specifications

Antigen TFEB
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene TFEB
Gene Accession No. P19484, Q9R210
Gene Alias TFEB; transcription factor EB; TCFEB; T-cell transcription factor EB
Gene Symbols TFEB
Host Species Rabbit
Immunogen Between 426 and 476
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21425, 7942
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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